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Perspectives

Natural compounds for treating pain

E. Russell Vickers

Figures

© MARILYN BARBONE/ STOCK.ADOBE.COM
© MARILYN BARBONE/ STOCK.ADOBE.COM

Abstract

The natural compounds found in fruit, vegetables and herbal medicines have emerging scientific evidence of efficacy and safety for treating pain, including neuropathic pain. In the associated field of regenerative medicine concerning amputation pain syndromes, these compounds can potentially enhance tissue regeneration by stem cell expansion and targeted differentiation.

Key Points

  • Natural pain-relieving compounds are found in fruit, vegetables and herbal medicines.
  • They exhibit high levels of safety, few side effects and increasing evidence of efficacy.
  • The major natural compound classes are polyphenols, polyamines and endocannabinoids.
  • Several of these compounds modulate novel pain therapies, such as stem cell treatment, by increasing normal stem cell growth and differentiation and inhibiting cancer stem cells.

Figures

© MARILYN BARBONE/ STOCK.ADOBE.COM
© MARILYN BARBONE/ STOCK.ADOBE.COM